The Hon. Greg Hunt MP
Minister for Health and Aged Care
The Morrison Government is investing more than $15 million in 19 innovative research projects that will drive better health care through the National Health and Medical Research Council (NHMRC) Development Grant scheme.
The grants will support researchers undertaking health and medical research within Australia at the proof-of-concept stage whose projects show potential for a commercial outcome within a foreseeable timeframe.
Minister for Health and Aged Care, Greg Hunt, said the funding would support the continued development of innovative products, processes, procedures and services and contribute to better health care in the future.
“Australia continues to be at the forefront of medical research and these projects have the potential to increase not only our understanding of diseases, but to also revolutionise their treatment,” Minister Hunt said.
“From the development of drugs to improve immunotherapy to methods to enhance the treatment of pancreatic cancers, these projects have the potential to significantly improve patient outcomes.”
“Our Government continues to provide unprecedented support to health and medical research, as we back our best and brightest researchers to transform today’s ideas into breakthrough treatments for the patients of tomorrow.”
Grants included in this announcement will advance the development of a range of health and medical innovations, including:
- A device that allows clinicians to assess a patient’s lung function so they can plan radiotherapy to minimise side effects and evaluate suitability for surgery.
- A new form of RNA-based treatment for patients with liver cancer.
- A compound that can prevent scarring caused by chemotherapy in pancreatic cancer patients which limits the effectiveness of subsequent rounds of treatment.
- A new device to open blocked coronary arteries (angioplasty) that targets drug delivery to the surface of a re-narrowed blood vessel, for safer and more effective treatment of vascular disease.
- A new, low-energy laser that rescues the light-sensitive film at the back of the eye to preserve central vision and prevent complete blindness from retinitis pigmentosa.
- A highly active antimalarial drug class with a known mechanism of action and the prerequisites to advance to human clinical trials.
NHMRC CEO Professor Anne Kelso said it was exciting to see these innovations making progress along the path to patient care.
“We know that commercial development of medical technologies can be challenging. These grants fill a critical gap in that pathway by supporting research teams to obtain the proof-of-concept data needed to attract a commercial partner,” Professor Kelso said.
|Title||Chief Investigators||Administering Institution||Budget|
|A First-In-Class Tumour Matrix Targeting Approach to Enhance Chemotherapy in Pancreatic Cancer||Assoc Prof Thomas Cox||University of New South Wales||$827,500.00|
|Development of a Novel Photo-Angioplasty Device for the Treatment of Occlusive Peripheral Vascular Disease||Assoc Prof Anthony Dear||Monash University||$808,505.00|
|Preventing reperfusion injury in stroke with an acutely dosed NK1R antagonist prodrug||Prof Jonathan Baell||Monash University||$653,527.20|
|Building Synthetic DNA Controls for Oxford Nanopore Sequencing.||Assoc Prof Timothy Mercer||The University of Queensland||$786,252.00|
|Developing HCK inhibitor drugs to improve immunotherapy||Prof Matthias Ernst||La Trobe University||$992,328.00|
|Targeting metabolism to correct fatty liver disease||Assoc Prof Kyle Hoehn||University of New South Wales||$621,083.00|
|Lung Ventilation Imaging: A new device to protect the lungs for cancer treatment||Prof Ricky O’Brien||University of Sydney||$1,075,714.00|
|Development of a non-invasive mucosal integrity diagnostic and ingestible capsule sampling tool targeting IBD gut health.||Dr Valerie Wasinger||University of New South Wales||$345,635.20|
|Developing a first-in-class therapeutic for chronic visceral pain using venom derived peptides||Prof Stuart Brierley||Flinders University||$998,858.88|
|Retinal Implant with Closed-loop, Multichannel Stimulation to Improve Visual Acuity||Assoc Prof Hamish Meffin||University of Melbourne||$1,141,581.50|
|Targeting the Achilles’ heel of multi-drug resistant Neisseria gonorrhoea with drugs that disrupt metal homeostasis||Prof Mark von Itzstein||Griffith University||$1,116,524.60|
|A novel RNA-based therapeutic for liver cancer||Prof Peter Leedman||University of Western Australia||$482,632.00|
|Rescuing cone photoreceptors in retinitis pigmentosa with laser-delivered photobiomodulation||Prof Robert Casson||The University of Adelaide||$525,106.00|
|Development of a novel topical serine protease inhibitor for tissue repair and inflammatory skin disease||Assoc Prof Mark Fear||University of Western Australia||$590,264.40|
|Development of a potent and fast acting antimalarial that is orally efficacious in vivo||Dr Brad Sleebs||The Walter and Eliza Hall Institute||$1,002,769.20|
|Developing FXIIa inhibitors as next-generation anticoagulants||Prof David Craik||The University of Queensland||$698,512.40|
|Development of a novel blood test that accurately predicts response to checkpoint therapy in cancer patients||Prof Barbara Fazekas de St Groth||University of Sydney||$571,216.00|
|Novel long-acting and orally delivered conotoxin-based peptides with both analgesic efficacy and disease modifying potential.||Dr Richard Clark||The University of Queensland||$948,644.00|
|c-FIND: Diagnosis of infections in minutes||Prof Marc Pellegrini||The Walter and Eliza Hall Institute||$868,752.00|